本片为《一条狗的使命》姊妹篇，讲述了狗狗贝拉穿越四百英里回家的故事。男主角卢卡斯在一座废弃建筑里偶遇幼犬贝拉。尽管他的母亲禁止养狗，他还是说服母亲将贝拉带回抚养，并把贝拉带到他工作的退伍军人医院，为病人们带去欢乐和慰藉。一次意外让长大的贝拉不慎走失，阴错阳差的与主人分隔两地。与主人分离的贝拉心急如焚，翻过雪山和草原，沿着落基山脉、跨越危机四伏的科罗拉多荒野，毅然踏上了未知而艰险的，长达四百英里的冒险归家旅程，只为回到主人卢卡斯身边，回到家里。
导演（1）
演员（28）
布莱斯来自大名鼎鼎的霍华德家族，其父是美国著名导演罗恩·霍华德，其母是女演员谢莉尔·霍华德，此外，布莱斯的祖父母和叔叔克林特·霍华德同样是电影工作者。 早在童年时代，布莱斯就曾在父亲罗恩的电影中露脸，其中就包括著名的《阿波罗13号》，然而真正让世人记住这个名字的电影是印度导演奈特·沙马兰的作品《灵异村》。2006年，两人再度合作的作品《水中女妖》无疑因《灵异村》的盛名而倍受关注。
英国青年演员，United Agents旗下艺人，曾在Farrer Theatre的舞台剧Macbeth中出演主角麦克白，出演过Kenneth Branagh剧院公司的舞台剧The Entertainer. 影视剧方面他在《霍华德庄园》里饰演Paul Wilcox, 在新版BBC迷你剧《小妇人》出演男主Laurie Laurence.
Alexandra Shipp is from Phoenix, Arizona and moved to Los Angeles to pursue an acting career at 17. She is best known for her role as KT Rush in the Belgian/American/British Teen Drama Mystery television series of Nickelodeon: House of Anubis. Alexandra is a talented singer/songwriter and is in the process of recording her first EP due out in early 2014.
艾什莉·贾德原名艾什莉·泰勒·辛米耐拉，1968年4月19日出生于美国加州。 艾什莉·贾德母亲和姐姐都是歌手，曾于肯塔基大学主修法文，1991年贾德进入演艺圈，1993年凭借《鲁比的天堂岁月》荣获美国独立精神奖最佳女主角，芝加哥影评人协会最佳新人奖。1996年因在电视电影《双面玛莲娜》荣获金球奖电视类最佳女主角提名。1999年随着《双重阴谋》的卖座成功，一跃成为好莱坞一线女星。也曾多次被《人物》杂志评选为“世界最美丽的50人”之一。 2002年，艾什莉·贾德与老搭档摩根·弗里曼合作推出惊悚片《极度重罪》。2004年则与凯文·克莱恩合演了记述作曲家柯尔·波特生平的音乐传记片《小可爱》。
爱德华·詹姆斯·奥莫斯（Edward James Olmos），1947年出生于加利福尼亚州，美国著名影视演员、导演及制片人。1964年，奥莫斯高中毕业后，在东洛杉矶学院学习戏剧表演。主演过电影罢工、黑帮大时代、天使在人间等。奥莫斯母亲埃莉诺，父亲佩德罗·奥莫斯，父亲曾经是焊工和邮递员。奥莫斯的父亲和母亲都是墨西哥人。孩提时，奥莫斯想当一个职业棒球手，少年时代，他的兴趣转向音乐，尤其是摇滚乐。
Michael Barrett \"Barry\" Watson (born April 23, 1974) is an American actor, known for his roles of Matthew \"Matt\" Camden on 7th Heaven, Brian Davis in What About Brian and Todd Deepler in Samantha Who?.
Career Gallagher is known for his television roles as Det. Joe Finn in Da Vinci\'s Inquest, the alcohol salesman in Entourage, Leon in The Line, Farhod the Fierce in Pair of Kings, and Ken Tanaka in Glee, and his film roles as Awkward Davies in Master and Commander: The Far Side of the World and Gary the bartender in Sideways. Gallagher also played Attila the Hun in Night at the Museum and its sequels, Chow in True Blood, Colquitt in Final Destination 3 Anderson in the movie Severed: Forest of the Dead, he also played the head of security, Hugo, in the short-lived series Endgame. He has also made guest appearances in Battlestar Galactica, Smallville, Hawaii Five-0 and Intelligence. Personal life Gallagher was born in Chilliwack, British Columbia, Canada. He is of Chinese and Irish descent.
John was born and raised in downtown Toronto to Italian parents who made the long journey to Canada to start a new life. He first caught the acting/filmmaking bug in Grade 8. It was then that Aiko Suzuki (sister of David Suzuki) came to his class and taught a course in super 8 filmmaking. John played his first leading role as a blind boy in a film shot in the then new Spadina subway station. Nevertheless, it would take some time and a diversion into athletics before John would return to his passion for the arts. John would eventually find his focus in athletics at Central Tech High School. John would go on to be part of the record breaking 4x100m relay team alongside Olympian Atlee Mahorn. It was his speed that would catch the attention of the football team and in his senior year he would be awarded an Athletic Scholarship to Simon Fraser University in Vancouver, BC. It was in the Simon Fraser Theater program that John\'s passion for acting was ignited. John would waste no time, and after 2 years at the University John made the move to New York to join his older brother Frank to further his studies and commit to acting as a life choice. By day John studied with acclaimed acting teacher Julie Bovasso. At night John would go to what he calls \"one of the greatest jobs I have ever talked my way into\" - an usher at the renowned Vivian Beaumont Theater in the beautiful Lincoln Center. Nightly, John would seat his audiences and then get lost in the magic of the theater as he quietly perched at the top of the stairs. John found his way back to Vancouver where he spent a few years doing plays, a variety of TV and film projects and eventually landed his first big Hollywood Feature Film- Alive. Soon after John was in Los Angeles for the Premiere of Alive, and quickly began landing roles, resulting in a permanent move to L.A. While in LA John co-wrote, produced and starred in the award winning independent film Break A Leg starring Molly Parker, Jennifer Beals, Sandra Oh, Kevi
Darcy Laurie是一名演员。2006年在电影《魔蝎女杀手》中饰演Lawrence Malishak； 2007年在电影《罪恶》中饰演Spoonie； 2008年在电影《大峡谷遗宝》中饰演Mexican Bartender；2012年在电影《成为莱德伍德》中饰演Jonno；2013年在电影《海军陆战队员3》中饰演Teddy。
亚历山德拉·西普（Alexandra Shipp），1991年7月16日出生于美国亚利桑那州凤凰城 ，美国女演员。主要作品有《鼠来宝：明星俱乐部》、《X战警：天启》。《新变种人》《x战警：黑凤凰》《悲剧女孩》《爱你，西蒙》等。她黑人女星特有的魅力，也常被网友用来和前任暴风女饰演者，影后“哈利贝瑞”相比。